2025 season · Week 6

Pregame

AI summary, sourced from 1 period article (ESPN AP)

The 49ers (4-1) travel to Raymond James Stadium for a 4:25 ET kickoff against the Tampa Bay Buccaneers (4-1). Brock Purdy remains out; Mac Jones makes his fifth straight start.

The Buccaneers play without Mike Evans, Chris Godwin and lead back Bucky Irving. Baker Mayfield enters 0-4 lifetime against the 49ers, averaging 169.3 passing yards per game in those four (his third-lowest mark for any opponent).

Mayfield has thrown 10 touchdowns to one interception through five games. The total is the projected highest-scoring 49ers game of the season.[1][2][3]

AI summary, sourced from 1 period article (ESPN AP)

There is a version of this football team built to win games like Sunday's, where the opposing QB historically struggles and the opponent is missing two All-Pro receivers. That version is 4-1 with most of its starting offense in walking boots.

Mac Jones started the season as a redemption story. Five weeks in he is a workhorse. He has played through a leg injury, played from behind, played without his top three receivers. Sunday is the fifth straight start.

The schedule turns from soft to soft to soft. The question for a banged-up team is whether it can stack four-quarter wins against opponents it should beat. Sunday is the first one.

AI summary, sourced from 1 period article (ESPN AP)

Week 6 is the NFC's last clean separator before bye weeks scramble the standings. The 49ers and Buccaneers enter as the only two teams projected at top-six seeds with serious injury concerns; both will be playing key absences. Around the NFC, Detroit and Philadelphia remain unbeaten. The NFC West sits clustered with the Rams and 49ers both 4-1. The Bucs' game against the 49ers is the headliner of an NFC South that has spent the last three years rebuilding from the Brady era and finally has a quarterback in Mayfield it trusts. A 49ers road win Sunday quietly becomes a tiebreaker piece in late January.

AI summary, sourced from 1 period article (ESPN AP)

Through five games the 49ers are 4-1 with a +8 point differential and the league's 5th-ranked scoring defense (17.4 ppg). Mac Jones has thrown for 1,142 yards through four-plus games on six touchdowns and three interceptions. Baker Mayfield has 1,283 passing yards through five with 10 TDs and 1 INT but a career 0-4 record against the 49ers, averaging 169.3 passing yards per game in those four (his third-lowest mark for any opponent). Vegas opens the Bucs as 3-point home favorites; the total sits at 47.5, projected as San Francisco's highest-scoring game of the year.

League standings entering Week 6

Standings as of kickoff, Week 6 (no future-game spoilers)

Around the league

  • Tied atop the league at 4-1: Buffalo Bills, Indianapolis Colts, Jacksonville Jaguars.
  • Still searching for win one: New York Jets.

AFC

AFC East

TeamRecStrk
Buffalo Bills4-1--
New England Patriots3-2--
Miami Dolphins1-4--
New York Jets0-5--

AFC North

TeamRecStrk
Pittsburgh Steelers3-1--
Cincinnati Bengals2-3--
Baltimore Ravens1-4--
Cleveland Browns1-4--

AFC South

TeamRecStrk
Indianapolis Colts4-1--
Jacksonville Jaguars4-1--
Houston Texans2-3--
Tennessee Titans1-4--

AFC West

TeamRecStrk
Denver Broncos3-2--
Los Angeles Chargers3-2--
Kansas City Chiefs2-3--
Las Vegas Raiders1-4--

NFC

NFC West

TeamRecStrk
San Francisco 49ers4-1--
Los Angeles Rams3-2--
Seattle Seahawks3-2--
Arizona Cardinals2-3--

NFC East

TeamRecStrk
Philadelphia Eagles4-1--
Washington Commanders3-2--
Dallas Cowboys2-2-1--
New York Giants1-4--

NFC North

TeamRecStrk
Detroit Lions4-1--
Minnesota Vikings3-2--
Green Bay Packers2-1-1--
Chicago Bears2-2--

NFC South

TeamRecStrk
Tampa Bay Buccaneers4-1--
Atlanta Falcons2-2--
Carolina Panthers2-3--
New Orleans Saints1-4--

Game video

▶ Open in YouTube San Francisco 49ers vs. Tampa Bay Buccaneers FULL GAME | 2025 NFL Season Week 6 · channel: Game series

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Game info

Roof
outdoors
Surface
grass
Weather
82°F, wind 10 mph
Stadium
Raymond James Stadium
Referee
Brad Rogers
QB matchup
Mac Jones vs Baker Mayfield
Vegas line
49ers -3.5
Over/Under
46.5

Score

Reveal through:

49ers 3, Tampa Bay Buccaneers 749ers 16, Tampa Bay Buccaneers 2049ers 19, Tampa Bay Buccaneers 2749ers 19, Tampa Bay Buccaneers 3049ers 19, Tampa Bay Buccaneers 30[1]

1234T
San Francisco 49ers31330316191919
Tampa Bay Buccaneers71373720273030

Scoring plays

Reveal each quarter as you watch, the next quarter stays hidden until you tap it.

Q1

TeamPlayScore
BuccaneersRachaad White 2 yard rush ( Chase McLaughlin kick)0-7
49ersEddy Piñeiro 52 yard field goal3-7

Q2

TeamPlayScore
49ersChristian McCaffrey 1 yard rush ( Eddy Piñeiro kick)10-7
BuccaneersSean Tucker 9 yard rush ( Chase McLaughlin kick)10-14
49ersEddy Piñeiro 54 yard field goal13-14
BuccaneersKameron Johnson 34 yard pass from Baker Mayfield (run failed)13-20
49ersEddy Piñeiro 42 yard field goal16-20

Q3

TeamPlayScore
49ersEddy Piñeiro 29 yard field goal19-20
BuccaneersTez Johnson 45 yard pass from Baker Mayfield ( Chase McLaughlin kick)19-27

Q4

TeamPlayScore
BuccaneersChase McLaughlin 45 yard field goal19-30

Recap

AI summary, sourced from 1 period article (ESPN AP)

Baker Mayfield threw for 256 yards and two touchdowns and the Tampa Bay Buccaneers beat the 49ers 30-19 at Raymond James Stadium to drop San Francisco to 4-2. Mayfield connected with Tez Johnson on a 34-yard touchdown to extend the lead in the second half; an earlier 45-yard touchdown to Kameron Johnson set the tone. Mac Jones threw for 347 yards but had two interceptions for the 49ers, who lost All-Pro linebacker Fred Warner to a broken and dislocated right ankle in the first quarter, an injury Kyle Shanahan said requires season-ending surgery.[1][2][3]

AI summary, sourced from 1 period article (ESPN AP)

Fred Warner went down in the first quarter. The 49ers' linebacker who has missed essentially no real time in his career walked off Raymond James Stadium in a cart with what Kyle Shanahan would later call a broken and dislocated ankle. Season-ending surgery. A franchise defensive cornerstone, gone from the 2025 season after one quarter of Week 6.

The game itself, by the end, felt incidental. Baker Mayfield, 0-4 against the 49ers entering, broke a third-and-14 in the fourth quarter on a scramble that drew MVP chants from the home crowd and rode that play to a 30-19 win. He threw for 256 and two scores. He earned the win.

The lasting story of the afternoon is not the score. It is the player. Christian McCaffrey, who shared a locker room with Warner since the day he arrived in San Francisco, summed it up cleanly: 'It is just heartbreaking.' Mac Jones, in his fifth straight start, said he was proud the team fought. Pride does not cover the absence the 49ers' defense is about to live with for the rest of the year. The Sundays from here are not going to look the same.

AI summary, sourced from 1 period article (ESPN AP)

Buccaneers 30, 49ers 19. Margin: -11. Six-game record: 4-2, -3 differential.

  • Mayfield: 17-of-23 for 256, 2 TD. 1-4 lifetime vs 49ers entering, now 1-4.
  • Mac Jones: 27-of-39 for 347, 2 INT.
  • Christian McCaffrey: 24 touches, 101 total yards, first 49ers rushing TD of the season on the team's 148th carry of the year.
  • TD passes: Mayfield to Kameron Johnson 45y, to Tez Johnson 34y.
  • Rachaad White: 2-yard rush to open scoring.
  • Fred Warner: season-ending broken/dislocated right ankle, Q1.
  • Bucs 5-1; 49ers 4-2, first divisional cushion gone.
AI summary, sourced from 1 period article (ESPN AP)

A 30-19 loss at Raymond James Stadium. The 49ers fall to 4-2.

How it unfolded

Rachaad White scored from the 2 to put Tampa Bay up 7-0 on the opening drive. The 49ers answered when McCaffrey scored from the 1 for the team's first rushing touchdown of the season, an answer that came on attempt 148. Mayfield connected with Kameron Johnson for a 34-yard score to push the Bucs ahead 20-13 late in the first half. The second half was the Mayfield show: a 45-yard touchdown to Tez Johnson, then the play that fans serenaded with 'MVP' chants, a third-and-14 scramble in the fourth quarter from the 41 in which Mayfield dodged a sack, escaped another defender, scrambled out of trouble, eluded more tackles and dove headfirst for a first down. The conversion led to the score that sealed it.

The turning point

The Mayfield scramble. With the game still in question and the 49ers within 20-19 early in the fourth quarter, the Buccaneers faced a third-and-14 at their 41. Mayfield made the kind of play this offense was not supposed to need. 'I was in disbelief like everybody else,' Todd Bowles said. 'He has a knack you can not teach.'

By the numbers

Mac Jones 27-of-39 for 347 yards, two interceptions. Mayfield 17-of-23 for 256 with two scores. McCaffrey 24 touches for 101 yards. Most of Mac Jones' yardage came in catch-up mode after the Buccaneers built their cushion.

Personnel watch

Fred Warner left in the first quarter and did not come back. Kyle Shanahan announced after the game that the ankle was broken and dislocated and that Warner would need season-ending surgery. The 49ers also played without Brock Purdy, Nick Bosa, Ricky Pearsall and Jauan Jennings. The list of absences is now long enough to read as the depth chart.

What it means

4-2 with the franchise linebacker out for the year. The schedule from here is at least kind on paper, but kindness on paper is not always kindness in practice when a defense has lost its captain. Atlanta on Sunday night next, then Houston.

Box score

Passing

PlayerC/AYdsTDIntRate
SFO
Mac Jones27/3934702
TAM
Baker Mayfield17/2325620

Rushing

PlayerAttYdsTDLong
SFO
Christian McCaffrey1754111
Mac Jones51305
TAM
Rachaad White1765110
Sean Tucker62519
Baker Mayfield314015

Receiving

PlayerRecYdsTDLong
SFO
Kendrick Bourne5142056
Jake Tonges658016
Christian McCaffrey757023
Demarcus Robinson244031
Marquez Valdes-Scantling222019
Kyle Juszczyk1909
Brian Robinson Jr.3804
Jauan Jennings1707
TAM
Kameron Johnson464134
Cade Otton551023
Sterling Shepard251036
Tez Johnson145145
Emeka Egbuka224017
Rachaad White321018

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